However, ART fails to eliminate integrated copies of HIV-1 proviral DNA from the host genome 1, 2. In the clinic, antiretroviral therapy (ART) restricts viral infection by stalling various steps of the viral life cycle.
According to UNAIDS, it is estimated that more than 36.7 million people worldwide are infected with the human immunodeficiency virus type one (HIV-1) and >5000 individuals worldwide are newly infected each day.
